Table 1a.
Characteristics of the 278 Patients from Institution 1, stratified by “poor” (mRS 0–3) and “good” (mRS 4–6) outcomes. Percentages are rounded to the nearest whole number. Footnotes are provided by variable names to indicate significant differences in medians between groups at an α level of .05 using Mood’s median test using the “RVAideMemoire” package in R33.
“Poor” outcome N = 204 |
“Good” Outcome N = 74 |
||
---|---|---|---|
Variable | Details | N (%) or Median [IQR] | |
Age, Years1 | Continuous | 66 [55.75 – 77.25] | 60 [49.25 – 70.00] |
Gender | Categorical | ||
Male | 90 (44.1) | 43 (58.1) | |
Female | 114 (55.9) | 31 (41.9) | |
Race | Categorical | ||
White | 104 (51) | 38 (51.4) | |
Black or African American | 91 (44.6) | 30 (40.5) | |
Asian | 3 (1.5) | 2 (2.7) | |
Native Pacific Islander | 4 (2) | 4 (5.4) | |
American Indian/Native Alaskan | 0 (0) | 0 (0) | |
Not Reported | 2 (0.9) | 0 (0) | |
ICH Score, Total | Ordinal | ||
0 | 39 (19.1) | 45 (60.8) | |
1 | 61 (29.9) | 24 (32.4) | |
2 | 53 (26) | 5 (6.8) | |
3 | 34 (16.7 | 0 (0) | |
>=4 | 17 (8.3) | 0 (0) | |
Glasgow Coma Scale | Ordinal | ||
13–15 | 111 (54.4) | 68 (91.9) | |
5–12 | 73 (35.8) | 6 (8.1) | |
3–4 | 20 (9.8) | 0 (0) | |
Intraventricular Hemorrhage | Categorical | ||
Yes | 105 (51.5) | 9 (12.2) | |
No | 99 (48.5) | 65 (87.8) | |
Large Hematoma Volume | Categorical | ||
At least 30 cc | 56 (27.5) | 2 (2.7) | |
Less than 30 cc | 148 (72.5) | 72 (97.3) | |
Initial Hematoma Volume, mL2 | Continuous | 12 [6.0 – 30.00] | 4 [1.4 – 11.35] |
Located in Infratentorial Region | Categorical | ||
Yes | 24 (11.8) | 10 (13.5) | |
No | 180 (88.2) | 64 (86.5) | |
Hematoma Expansion, mL3 | Continuous | 0.185 [−1.23 – 3.05] | −0.10 [−0.38 – 0.28] |
Seizure | Categorical | ||
Has had a seizure | 10 (4.9) | 3 (4.1) | |
Has not had a seizure | 194 (95.1) | 71 (95.9) | |
Reversal of Anticoagulation | Categorical | ||
Presence of reversal | 14 (6.9) | 5 (6.8) | |
No reversal | 190 (93.1) | 69 (93.2) | |
Desmopressin | Categorical | ||
Given | 29 (14.2) | 9 (12.2) | |
Not given | 175 (85.8) | 65 (87.8) | |
Historical Modified Rankin, | Ordinal | ||
0 | 151 (74) | 62 (83.8) | |
1 | 18 (8.8) | 7 (9.4) | |
2 | 7 (3.4) | 3 (4.1) | |
3 | 8 (3.9) | 2 (2.7) | |
4 | 19 (9.3) | 0 (0) | |
5 | 1 (0.5) | 0 (0) | |
Novel Oral Anticoagulant | Categorical | ||
Given | 0 (0) | 1 (1–4) | |
Not given | 204 (100) | 73 (98.6) | |
Warfarin Use | Categorical | ||
Usage | 23 (11.3) | 5 (6.8) | |
No usage | 181 (88.7) | 69 (93.2) | |
International Normalized Ratio | Continuous | 1.1 [1 – 1.2] | 1.1 [1 – 1.2] |
Statin | Categorical | ||
Usage | 33 (16.2) | 11 (14.9) | |
No usage | 171 (83.8) | 63 (85.1) | |
Aspirin Use Prior to ICH | Categorical | ||
Usage | 70 (34.3) | 24 (32.4) | |
No usage | 134 (65.7) | 50 (67.6) | |
Diabetes by History | Categorical | ||
Diagnosis | 35 (17.2) | 15 (20.3) | |
No diagnosis | 169 (82.8) | 59 (79.7) | |
Hypertension by History | Categorical | ||
Diagnosis | 148 (72.5) | 52 (70.3) | |
No diagnosis | 56 (27.5) | 22 (29.7) |
χ2 (1, 278) = 4.68 , p = .03
χ2 (1, 278) = 17.46 , p < .001
χ2 (1, 278) = 8.12 , p = .004