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. 2020 Nov 6;11:5621. doi: 10.1038/s41467-020-19514-1

Fig. 5. In vitro splicing assay of IgM pre-mRNA with 7,8-dimethoxyperphenazine (Cmp7), Cmp8 and Cmp9.

Fig. 5

a 7,8-dimethoxyperphenazine (Cmp7), Cmp8 and Cmp9 abolish splicing of IgM pre-mRNA at 2 mM, 1.5 mM and 2 mM respectively. b Separation of spliceosomal complexes on an agarose gel. For Cmp7, splicing inhibition (a and b) was replicated in three independent experiments, and for Cmp8 and Cmp9, it was performed once. The uncropped gel images are included in the Source Data file.