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. 2020 Nov 7;10:136. doi: 10.1186/s13550-020-00726-x

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — [¹⁸F]FDG SUV_peak within interscapular BAT of fasted male mice after NE injection. SUV_peak is plotted for each genotype. Means (short) and standard deviations (long) for each group are represented by horizontal gray bars. With fasting, a statistically significant difference between male WT (blue) and KO (white) SUV_peak was observed (p = 0.03). However, the WT and KO SUV_peak ranges still overlapped and a clear SUV threshold to differentiate animals with very different thermogenic capacity cannot be established, despite animal fasting