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. 2020 Nov 7;10:136. doi: 10.1186/s13550-020-00726-x

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — Effect of NE injection on SUV_peak for fasted male mice. SUV_peak is plotted for each genotype with (w/NE) and without (w/o NE) NE injection. There is a significant increase in the SUV_peak in the WT mice with NE injection (p < 0.001). On the other hand, SUV_peak in KO mice seems to either stay the same or decrease with NE injection. In addition, the average SUV_peak in KO mice without NE stimulation is much higher than that in WT mice (p = 0.046)