Table 2.
Screening of the hub genes by constructing protein–protein interaction networks
| Node_name | Degree | Closeness | Betweenness | Clustering coefficient |
|---|---|---|---|---|
| Sorted by degree (top 10) | ||||
| MMP9 | 29 | 57.16825 | 2680.223 | 0.27833 |
| IL2 | 26 | 53.91349 | 1035.989 | 0.44615 |
| ITGAM | 25 | 53.56349 | 870.1263 | 0.42667 |
| IL1B | 24 | 52.61349 | 619.9493 | 0.42754 |
| SELL | 22 | 51.23016 | 372.9203 | 0.52381 |
| CTLA4 | 22 | 50.98016 | 258.224 | 0.55411 |
| IFNG | 21 | 52.55159 | 1285.687 | 0.55238 |
| CCR5 | 21 | 50.14683 | 131.4213 | 0.63333 |
| CCL3 | 17 | 48.24683 | 147.8977 | 0.66912 |
| CCL20 | 17 | 47.39683 | 55.42792 | 0.77206 |
| Sorted by betweenness (top 10) | ||||
| IGF2 | 12 | 48.47976 | 5251.501 | 0.15152 |
| OLA1 | 4 | 37.37619 | 4008.284 | 0.16667 |
| BBS10 | 8 | 33.84524 | 3962 | 0.10714 |
| MMP9 | 29 | 57.16825 | 2680.223 | 0.27833 |
| BBS7 | 3 | 27.33214 | 2352 | 0.33333 |
| KIFAP3 | 2 | 23.96667 | 2178 | 0 |
| ZNF608 | 6 | 23.725 | 2064 | 0.06667 |
| MAPK14 | 15 | 49.68492 | 1416.393 | 0.26667 |
| IFNG | 21 | 52.55159 | 1285.687 | 0.55238 |
| IL2 | 26 | 53.91349 | 1035.989 | 0.44615 |