Table 1. Hematological laboratory investigations of the study population.
| Characteristics | Median | IQR | Mean | + SD | p-value |
|---|---|---|---|---|---|
| Hemoglobin baseline, g/dL | 11.45 | 1.50 | 9.8 | 1.3 | < 0.001* |
| Hemoglobin nadir, g/dL | 7.25 | 1.20 | 7.2 | 0.9 | |
| WBC baseline, ×109/L | 8.40 | 6.50 | 8.9 | 3.4 | < 0.002* |
| WBC nadir, ×109/L | 7.20 | 4.70 | 6.8 | 2.5 | |
| Lymphocytes count baseline, ×109/L | 2.70 | 0.90 | 2.6 | 0.8 | < 0.001* |
| Lymphocytes count maximum, ×109/L | 3.70 | 1.80 | 4.1 | 2.0 | |
| Platelets count baseline, ×109/L | 313.00 | 233.00 | 350.6 | 252.4 | < 0.001* |
| Platelets count nadir, ×109/L | 238.50 | 232.00 | 285.2 | 207.9 | |
| ANC basaline, ×109/L | 4.20 | 1.60 | 3.9 | 0.9 | 0.273* |
| ANC nadir, ×109/L | 2.60 | 1.60 | 2.5 | 1.2 | |
| Reticulocyte basaline, ×109/L | 214.50 | 230.90 | 223.1 | 129.2 | < 0.005* |
| Reticulocyte nadir, ×109/L | 169.50 | 84.00 | 172.0 | 155.2 | |
| HbS, % | 85.10 | 7.00 | 86.3 | 3.8 | |
| HbF, % | 8.00 | 9.40 | 8.3 | 4.7 |
IQR: inter quartile range; SD: standard deviation; WBC: white blood cell; ANC: absolute neutrophil count; HbS: sickle cell hemoglobin; HbF: fetal hemoglobin. *Statistically significant (Wilcoxon signed ranks test).