Table 4.

Studies that investigated the therapeutic effects of resveratrol on schizophrenia

Disease	Dose of resveratrol	Model	Findings	Publish year	Ref
Animal studies
Schizophrenia	200 and 400 mg/kg	In vivo	reduced mean episodes of rearing and mean climbing scores	2017	[119]
MK-801-induced schizophrenia	40 mg/kg or 80 mg/kg	In vivo	Increased expression of SIRT1 and BDNF, decreased oxidative stress	2020	[134]
Schizophrenia	20 mg/kg	In vivo	Decreased VCMs	2017	[135]
MIA-induced schizophrenia	40 mg/kg	In vivo	Ameliorated hyperlocomotion and social behavior	2020	[136]
Human studies
Schizophrenia	200 mg/day	Human	No significant changes	2016	[137]
Schizophrenia	200 mg/day	Human	No significant changes	2016	[138]