Table 2. Effect of W.somnifera root extract on hydrogen peroxide, hydroxyl radical and lipid peroxidation in the cortex of control and sleep deprived rats.
Parameters | Normal control | Large platform control | Sleep Deprived rats | W.somnifera treated Sleep deprived rats | P Value |
H2O2 | 1.69±0.13 | 2.89 ±0.3a | 4.78 ±0.11a,b | 1.97 ±0.22a,b,c | <0.0017 |
LPO | 15± 1 | 22 ±2a | 28±1 a,b | 16 ±1 a,b,c | <0.0228 |
OH | 18±2.5 | 27 ±1.5 a | 38±2 a,b | 18 ±1.5 a,b,c | <0.0054 |
P value <0.05 statistically significant. |