Table 2. Genotypes and susceptibility pattern of MRSA infections observed at KAASH, Taif-Saudi Arabia, 2012.
Isolate | Spa-type | MLST | CC | PVL | Site | Type of infection | Resistant to |
A11 | t304 | 2882 | Negative | SST | CAI | - | |
A34 | Nasal | Colonization | |||||
A3 | 6 | 45 | Blood | HAI | |||
A4 | Positive | SST | CAI | ||||
A21 | 2882 | Negative | Nasal | Colonization | Intermediate susceptible to linezolid and vancomycin | ||
F21 | t311 | 5 | 45 | Cli | |||
F2 | t2770 | 97 | Blood | HAI | Fa | ||
F7 | Positive | SST | Fa | ||||
A2 | t044 | 80 | 80 | BURN | Fa | ||
A7 | t4573 | 22 | 22 | Negative | SST | CAI | Cip |
F14/F15 | Positive | HAI | Cip | ||||
A23 | SSI | Cip | |||||
A30 | Cip, Tr | ||||||
F16 | t748 | SST | CAI | Cip, Tr | |||
A32 | t5716 | Negative | Nasal | Colonization | Cli, Tr | ||
F23 | t223 | Tr, Te | |||||
F13 | t044 | 80 | 80 | Positive | SST | HAI | Fa, Te |
F20 | CAI | Fa, Te | |||||
F9 | t131 | Fa, Te | |||||
A5 | t037 | 239 | 8 | Fa, Te | |||
A29/A13 | t267 | 97 | Negative | Nasal | Colonization | Fa, Te, Gan | |
A28 | SSI | HAI | Fa, Te, Gen | ||||
C3 | t4573 | 22 | 22 | Positive | PNEU | HAI | Cli, Cip, Tr, Gen, Ery |
A15/A22 | t363 | 241 | 8 | Negative | BURN | Cli, Fa, Cip, Tr, Te, Gen, Ery, Mu | |
A27 | Cli, Fa, Cip, Tr, Te, Gen, Ery, | ||||||
A: King Abdul Aziz Specialist Hospital, F: King Faisal Hospital, C: Children Hospital C, CC: clonal complex, HAI: hospital acquired infection, CA: community acquired infection, SST: skin soft tissue, Cli: clindamycin, Fa: fucidic acid, Cip: ciprofloxacin, Tr: trimethobrium, Te: tetracycline, Gen: gentamicin, Ery: erythromycin, Mu: muperocin, Clo: chloramphenicol, Ref: refampicin. The table describes the genotypes and distribution of MRSA infections. There is a diversity of CC distribution in the study. Majority of strain type t4573, MLST 22, CC22 harboured PVL gene with different in susceptibility pattern to antimicrobial agents. However strain t363, MLST 241, CC8 doesn't harbour PVL but resistant to many antimicrobial agents. |