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. Author manuscript; available in PMC: 2020 Nov 9.
Published in final edited form as: Int J Cancer. 2019 Oct 25;147(2):361–374. doi: 10.1002/ijc.32727

Table 4a:

Pooled associations between socio-demographic, geographical and behavioural factors with chronic conditions (≥2 (multimorbidity) vs. <2) in women newly diagnosed with breast cancer.

Characteristics < 2 chronic conditions N=1280 ≥2 chronic conditions (multimorbidity) N=1001 Bivariate analysis OR (95% CI) P value
Age in years, mean ± SD 54.4 ± 15.0 58.4 ±13.0 1.02 (1.01–1.03) <0.001*
Ethnicity (%)
Black 976 (76.2%) 778 (77.7%) 1.00 (Referent)
Asian 130 (10.2%) 131 (13.1%) 1.26 (0.97–1.64) <0.001*
Mixed 56 (4.4%) 49 (4.9%) 1.10 (0.74–1.63)
White 118 (9.2%) 43 (4.3%) 0.46 (0.32–0.66)
Marital status (%)
Married/co-habiting 513 (40.2%) 348 (34.9%) 1.00 (Ref) 0.010*
Unmarried 763 (59.8%) 648 (65.1%) 1.25 (1.05–1.49)
Highest level of education (%)
Primary education and below 324 (24.4%) 303 (30.7%) 1.00 (Referent) 0.006*
Secondary education and above 949 (74.6%) 684 (69.3%) 0.77 (0.64–0.93)
Employment status (%)
Unemployed 921 (71.9%) 775 (77.4%) 1.00 (Referent) 0.003*
Employed 359 (28.1%) 226 (22.6%) 0.75 (0.62–0.91)
Household socio-economic status (score 0–6), median (IQR) 3(2–5) 4(2–5) 1.02 (0.97–1.07) 0.488
Hospital site (%)
Soweto, Johannesburg 472 (36.9%) 323 (32.3%) 1.00 (Referent) <0.001*
Central Johannesburg 318 (24.8%) 193 (19.3%) 0.89 (0.71–1.11)
KZN Durban 211 (16.5%) 225 (22.5%) 1.56 (1.23–1.97)
KZN Pietermaritzburg 240 (18.8%) 222 (22.2%) 1.35 (1.07–1.70)
KZN rural 39 (3.1%) 38 (3.8%) 1.42 (0.89–2.28)
Residential distance from hospital site (km), median (IQR) 19.9 (8.7–39.5) 21.8 (9.1–48.1) 1.00 (1.00–1.01) 0.033*
Have you ever consumed alcohol? (%)
No 1004 (78.4%) 828 (82.7%) 1.00 (Ref) 0.011*
Yes 276 (21.6%) 173 (17.3%) 0.76 (0.62–0.94)
Have you ever smoked? (%) 0.044*
No 1106 (86.4%) 893 (89.2%) 1.00 (Ref)
Yes 174 (13.6%) 108 (10.8%) 0.77 (0.60–0.99)

OR (Odds ratio) = odds of reporting ≥2 chronic conditions compared with <2 chronic conditions,

*

variables significant at p<0.05.

a

HSES: Household socio-economic status (possessions) score determined from: (home ownership=1, motor vehicle=1, microwave=1, washing machine=1, flush toilet=1, indoor running water=1) Denominator= 6 (1 for Yes, 0 for No), KZN (KwaZulu-Natal), SD (standard deviation), IQR (interquartile range), km (kilometres)