Table 1.

Threshold (ng/ml) for CNS bioactivity of bacterial components.

Component	Leukocytosis	Edema
Gram negative
LPS + PG	5	5
LPS	10	100
PG	100	1
Gram positive
LTA + PG	100	10
LTA	500	–
PG-TA w/stems	20	100
PG	100	–
Stem peptides	10,000	1
TA free	500	10,000

Compiled from: (Tuomanen et al., 1985a,b; Tomasz and Saukkonen, 1989; Burroughs et al., 1992, 1993a,b; Weber et al., 2003a,b).