Table 3.

NMR metabolites with differential colonic levels between pigs under high (HSC) and low (LSC) sanitary conditions.

Metabolite	ppma	p-value	HSCb	LSCc	FC HSC/LSC
Inosine	8.22	0.019	1,569,004	1,262,322	1.24
Urocanic acid (overlaps with uridine)	7.86	0.024	1,507,445	1,219,191	1.24
Cytidine	7.82	0.030	1,272,221	1,090,030	1.17
Uracil-derivative	7.66	0.001	1,051,337	755,404	1.39
Phenylalanine	7.38	0.001	5,326,128	3,849,696	1.38
Phenylalanine	7.30	0.006	8,785,567	6,387,726	1.38
Gallic acid	7.02	0.003	1,758,394	1,192,498	1.47
Gentisic acid	6.98	0.000	3,135,842	1,958,977	1.60
Cresol	6.94	0.001	2,622,976	1,760,954	1.49
Tyrosine	6.90	0.002	2,908,448	1,849,886	1.57
Fumaric acid	6.54	0.042	678,028	525,169	1.29
Orotic acid	6.18	0.004	423,688	294,373	1.44
Inosine derivative	6.10	0.006	571,384	418,067	1.37
Maleic acid	6.02	0.000	1,369,948	1,154,823	1.19
Uracil	5.70	0.001	526,920	378,035	1.39
Glucosamine (tentative)	5.54	0.049	1,014,960	841,786	1.21
Sucrose	5.42	0.034	734,954	597,302	1.23
Asparagine	2.90	0.000	8,647,401	6,296,110	1.37
Asparagine	2.86	0.008	10,288,172	8,449,148	1.22
Succinate	2.42	0.000	16,927,583	11,079,148	1.53
Glutamic acid	2.38	0.015	33,766,106	24,645,419	1.37
Hydroxybutyric acid	2.34	0.011	36,311,422	29,279,850	1.24
n-valerate	1.58	0.005	17,909,947	13747776	1.30
Butyrate	1.54	0.004	81,290,463	58,211,276	1.40
Butyrate	0.90	0.000	68,198,492	46,297,287	1.47

^aBin number of the NMR spectra.

^bHigh sanitary condition.

^cLow sanitary condition.

Metabolite intensities were corrected for sample weight. All metabolites are higher in HSC then in LSC pigs. Metabolites are ranked by concentration.