Table 3.
Linear associations of total magnesium intake with cognitive impairment status stratified by selected factors, NHANES, 2011-2014
| Total Magnesium Intake (mg/day) |
Low (n= 583) |
High (n = 1,883) |
β (95% CI)ǂ |
|---|---|---|---|
| Male | |||
| Q1 <232 | 130 | 193 | Referent |
| Q2 232-310 | 91 | 194 | 1.03 (−2.06, 4.12) |
| Q3 311-412 | 44 | 235 | 3.42 (0.91, 5.93) |
| Q4 >412 | 62 | 258 | 2.91 (−0.52, 6.34) |
| p trend | 0.61 | ||
| Female | |||
| Q1 <232 | 133 | 350 | Referent |
| Q2 232-310 | 62 | 269 | 3.20 (0.42, 5.99) |
| Q3 311-412 | 35 | 215 | 3.80 (0.82, 6.77) |
| Q4 >412 | 26 | 169 | 5.61 (1.58, 9.63) |
| p trend | 0.01 | ||
| p interaction | 0.45 | ||
| Non-Hispanic White | |||
| Q1 <232 | 82 | 280 | Referent |
| Q2 232-310 | 49 | 266 | 2.53 (0.13, 4.95) |
| Q3 311-412 | 19 | 268 | 4.40 (1.97, 6.84) |
| Q4 >412 | 29 | 259 | 4.97 (1.37, 8.57) |
| p trend | 0.04 | ||
| Other Race/Ethnicity 1 | |||
| Q1 <232 | 181 | 263 | Referent |
| Q2 232-310 | 104 | 197 | 1.40 (−1.02, 3.81) |
| Q3 311-412 | 60 | 182 | 2.10 (0.21, 4.00) |
| Q4 >412 | 59 | 168 | 0.55 (−3.24, 4.33) |
| p trend | 0.51 | ||
| p interaction | 0.31 | ||
| Low/No Physical Activity | |||
| Q1 <232 | 196 | 335 | Referent |
| Q2 232-310 | 110 | 257 | 2.01 (−0.90, 4.92) |
| Q3 311-412 | 49 | 222 | 4.85 (1.26, 8.44) |
| Q4 >412 | 64 | 178 | 3.91 (−0.43, 8.26) |
| p trend | 0.04 | ||
| Moderate/High Physical Activity | |||
| Q1 <232 | 67 | 208 | Referent |
| Q2 232-310 | 43 | 206 | 3.17 (1.32, 5.03) |
| Q3 311-412 | 30 | 228 | 3.66 (1.63, 5.70) |
| Q4 >412 | 24 | 249 | 5.68 (2.66, 8.70) |
| p trend | <0.01 | ||
| p interaction | 0.17 | ||
| Serum 25(OH)D level (<50 nmol/L) | |||
| Q1 <232 | 85 | 140 | Referent |
| Q2 232-310 | 34 | 67 | −0.31 (−3.11, 2.48) |
| Q3 311-412 | 18 | 69 | 1.23 (−3.84, 6.31) |
| Q4 >412 | 19 | 45 | 0.86 (−6.54, 8.25) |
| p trend | 0.72 | ||
| Serum 25(OH)D level (>=50 nmol/L) | |||
| Q1 <232 | 178 | 403 | Referent |
| Q2 232-310 | 119 | 396 | 2.87 (0.52, 5.21) |
| Q3 311-412 | 61 | 381 | 4.45 (1.91, 7.00) |
| Q4 >412 | 69 | 382 | 4.77 (1.08, 8.46) |
| p trend | <0.01 | ||
| p interaction | 0.68 | ||
ǂ
Adjusted for age, sex, race/ethnicity, BMI, smoking status, activity, alcohol use, total calcium intake, history of cancer, education, season of exam, history of heart attack, diabetes status, history of stroke, total energy intake and serum 25(OH)D levels.
1
Other race/ethnicity: included non-Hispanic Black, Hispanic, non-Hispanic Asian, and Other Race.