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. 2020 Nov 8;11(11):960. doi: 10.1038/s41419-020-03143-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — M⁶A plays diverse roles in different cancer, and even plays the opposite roles in a type of cancer. On the on hand, m⁶A promotes tumor progression by increasing oncogene expression and decreasing tumor suppressor gene expression. On the other hand, m⁶A suppresses tumor progression in opposite ways. Specific functions of m6A in the main text.