Table I.
Various Types of Solid Dispersions and Their Relative Potential for Stability and Solubility Improvement
| SN. | API state | Carrier state | Phase solubility | SD subtype | Stability | Solubility |
|---|---|---|---|---|---|---|
| 1 | Crystal | Crystal | No | Solid suspension | +++ | ++ |
| 2 | Crystal | Crystal | Yes | Eutectics | +++ | + |
| 3 | Crystal | Amorphous | No | Solid suspension | +++ | ++ |
| 4 | Amorphous | Crystal | No | Solid suspension | + | +++ |
| 5 | Amorphous | Crystal | Yes | Solid solution | +++ | +++ |
| 6 | Amorphous | Amorphous | No | Glass suspension | + | +++ |
| 7 | Amorphous | Amorphous | Yes | Glass solution | +++ | +++ |
Part of the classification has been reproduced from the reference (23)