Table 1.
Demographic and clinical characteristics of patients in the hyperhidrosis and control groups
| Demographic and clinical characteristics | Control group (n = 137,451) | Hyperhidrosis group (n = 44,484) | p valuea |
|---|---|---|---|
| Mean age, years (SD) | 40.2 (16.9) | 36.5 (16.5) | < 0.001 |
| Female, n (%) | 76,930 (56.0%) | 26,028 (58.5%) | < 0.001 |
| US census region, n (%) | |||
| Northeast | 15,786 (11.5%) | 5517 (12.4%) | < 0.001 |
| Midwest | 42,254 (30.7%) | 13,522 (30.4%) | 0.056 |
| South | 57,056 (41.5%) | 17,843 (40.1%) | < 0.001 |
| West | 22,322 (16.2%) | 7595 (17.1%) | < 0.001 |
| Other | 33 (0.0%) | 7 (0.0%) | 0.205 |
| Comorbid conditions, n (%) | |||
| Respiratory infections | 42,227 (30.7%) | 17,330 (39.0%) | < 0.001 |
| Other lower respiratory infections | 20,785 (15.1%) | 8840 (19.9%) | < 0.001 |
| Other upper respiratory infections | 19,394 (14.1%) | 8029 (18.1%) | < 0.001 |
| Other gastrointestinal disorders | 13,438 (9.8%) | 6310 (14.2%) | < 0.001 |
| Other skin disordersb | 28,187 (20.5%) | 13,734 (30.9%) | < 0.001 |
| Other connective tissue disorders | 33,509 (24.4%) | 12,745 (28.7%) | < 0.001 |
SD Standard deviation
ap values were computed with clustering, with the Z test using robust standard errors in an ordinary least squares regression analysis for continuous measures, and the Rao-Scott test for binary measures
bA total of 172 skin conditions were identified in this category that applied to this patient sample. The most common condition was “other acne” (n = 4025, or 29.3% of patients identified with “other skin disorders”); diagnosis codes referring to acne were identified in 4865 patients, or 35.4% of patients identified with “other skin disorders”