Table 4.
Logistic regression model: adjusted odds of depression and/or anxiety
Odds ratio | 95% Confidence interval | p value | |
---|---|---|---|
Dependent variable: depression and/or anxiety, 12-month follow-up perioda,b | |||
Independent variables | |||
Hyperhidrosis cohort (reference: control cohort) | 1.76 | 1.72–1.80 | < 0.001 |
Comorbid conditions | |||
Respiratory infections | 1.28 | 1.25–1.31 | < 0.001 |
Other lower respiratory infections | 1.43 | 1.40–1.48 | < 0.001 |
Other upper respiratory infections | 1.24 | 1.21–1.28 | < 0.001 |
Other gastrointestinal disorders | 1.82 | 1.77–1.88 | < 0.001 |
Other skin conditions | 1.20 | 1.17–1.23 | < 0.001 |
Female gender (reference: male) | 1.75 | 1.71–1.79 | < 0.001 |
Age (years) | |||
< 9 | 0.16 | 0.14–0.19 | < 0.001 |
9–17 | 0.37 | 0.36–0.38 | < 0.001 |
18–24 | 0.64 | 0.62–0.67 | < 0.001 |
25–34 | 0.78 | 0.76–0.80 | < 0.001 |
≥ 35 | ref | – | – |
aRegression model was fitted for hyperhidrosis and control cohorts
bLogistic model was also estimated with an indicator of a match between hyperhidrosis and control cohorts with no change to model results. Observations used = 44,484 (hyperhidrosis); 137,451 (controls)