Table 3.
Summary of patient feedback on items from the preliminary P-SIM (N = 15)
| Concept (worst severity in P-SIM) | Frequency of report during concept elicitation, n (%) | Bothersome ratinga | Severity ratingb | ||
|---|---|---|---|---|---|
| Frequencyc, n (%) | Average, mean (SD) | Frequencyc, n (%) | Average, mean (SD) | ||
| 1. Skin itching | 15 (100.0) | 15 (100.0) | 7.7 (2.8) | 12 (80.0) | 8.3 (3.8) |
| 2. Skin redness | 15 (100.0) | 13 (86.7) | 8.2 (3.4) | 9 (60.0) | 5.9 (3.4) |
| 3. Skin pain | 8 (53.3) | 8 (53.3) | 7.5 (4.3) | 7 (46.7) | 7.3 (4.1) |
| 4. Skin burning | 6 (40.0) | 4 (26.7) | 8.5 (3.9) | 2 (13.3) | 9.0 (3.2) |
| 5. Skin scaling | 15 (100.0) | 10 (66.7) | 8.1 (4.3) | 5 (33.3) | 6.6 (3.5) |
| 6. Skin stingingd | 7 (46.7) | 1 (6.7) | 8.0 (2.1) | 1 (6.7) | 8.0 (2.1) |
| 7. Skin cracking | 12 (80.0) | 10 (66.7) | 7.5 (4.4) | 6 (40.0) | 6.5 (3.7) |
| 8. Skin flakingd | 15 (100.0) | 12 (80.0) | 8.2 (3.9) | 9 (60.0) | 7.8 (4.2) |
| 9. Skin dryness | 15 (100.0) | 12 (80.0) | 7.7 (3.7) | 7 (46.7) | 7.4 (4.1) |
| 10. Skin irritation | 11 (73.3) | 7 (46.7) | 7.0 (3.9) | 6 (40.0) | 6.8 (3.9) |
| 11. Skin sensitivity | 5 (33.3) | 5 (33.3) | 8.0 (4.0) | 2 (13.3) | 7.0 (2.5) |
| 12. Skin lesions | 8 (53.3) | 1 (6.7) | 9.0 (2.3) | 1 (6.7) | 2.0 (0.5) |
| 13. Skin thickening | 12 (80.0) | 6 (40.0) | 6.7 (3.8) | 4 (26.7) | 6.8 (3.1) |
| 14. Sleep lossd | 12 (80.0) | 8 (53.3) | 7.1 (4.2) | – | – |
| 15. Fatigue | 2 (13.3) | 1 (6.7) | 8.0 (2.0) | – | – |
| 16. Feelings of embarrassment | 7 (46.7) | 3 (20.0) | 7.0 (2.9) | – | – |
| 17. Avoid doing usual activitiesd | 9 (60.0) | 4 (26.7) | 5.0 (2.9) | – | – |
| 18. Personal relationshipsd | 11 (73.3) | 7 (46.7) | 6.4 (3.9) | – | – |
| 19. Choice of clothing | 15 (100.0) | 14 (93.3) | 6.3 (3.0) | – | – |
P-SIM psoriasis symptoms and impacts measure, SD standard deviation
aOn a scale of 0 to 10, where 0 = not bothersome at all and 10 = extremely bothersome
bOn a scale of 0 to 10, where 0 = no [sign/symptom] and 10 = [sign/symptom] as bad as you can imagine
cIn some cases, the N providing a bothersome/severity rating does not equal the total number of patients reporting this concept. These instances occurred because (1) the patient was not asked to provide a rating because of time constraints and/or interviewer’s discretion or (2) the patient’s response was found to be inconclusive during analysis
dThis item was ultimately removed from the final 14-item P-SIM