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. 2020 Oct 26;11:589010. doi: 10.3389/fimmu.2020.589010

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Copyright © 2020 Zhang, Zhu, Su, Cao, Li, Wei, Huang, Zheng, Li, Chen, Liu, Xia, Wu and He

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relationship between rs179010C/T and clinical parameters in AHI patients with rapid/slow progress. (A–H) There are four clinical parameters including, ICD4 (initial CD4 T cells) (A, E), CD4/CD8 (the ratio of CD4 versus CD8 T cells) (B, F), viral load (C, G), and set point (D, H). The y axis indicates the values of these four respective parameters. The x axis, indicates two patient groups with TLR7 rs179010C/T allele. The text on the top of each picture represents AHI-rapid/slow patients. Each dot represents an MSM individual, (●) represents individuals of AHI-rapid/slow progress with TLR7 rs179010C allele. (■) represents individuals of AHI-rapid/slow progress with TLR7 rs179010T allele. *indicates P < 0.05; P < 0.01 and P < 0.001.