Table 3.
The allele frequencies of three TLR7 SNPs in patients with AHI/CHI and controls.
| Allele frequencies | AHI Cases, N (%) | CHI Cases, N (%) | Controls, N (%) | P1 value/OR (95% CI) | P2 value/OR (95% CI) |
|---|---|---|---|---|---|
| rs179010 | N = 157 | No = 113 | N = 196 | ||
| C | 111(70.7) | 71(62.8) | 116(59.2) | 1 | 1 |
| T | 46(29.3) | 42(37.2) | 80(40.8) | 0.002/0.664 (0.513-0.860) | 0.889/1.021 (0.765-1.362) |
| rs2074109 | N = 157 | No = 113 | N = 196 | ||
| T | 148(94.3) | 106(93.8) | 186(94.9) | 1 | 1 |
| C | 9(5.7) | 7(6.2) | 10(5.1) | 0.704/0.907(0.548-1.502) | 0.612/1.154(0.664-2.004) |
| rs179009 | N=157 | No=113 | N=196 | ||
| A | 138(87.9) | 83(73.5) | 168(85.7) | 1 | 1 |
| G | 19(12.1) | 30(26.5) | 28(14.3) | 0.193/0.792(0.557-1.125) | 0.016/1.526(1.081-2.153) |
P1/2 value was adjusted for age by logistic regression between AHI/CHI cases and controls.
AHI, acute HIV-1 infection: CHI, chronic HIV-1 infection.
Bold value indicates the statistical significance.