Table 4.
The allele frequencies of three TLR7 SNPs in patients with AHI-rapid/slow and controls.
| Allele frequencies | AHI-rapid, N (%) | AHI-slow, N (%) | Controls, N (%) | P1 value/OR (95% CI) | P2 value/OR (95% CI) |
|---|---|---|---|---|---|
| N = 54 | N = 60 | N = 196 | |||
| TLR7 rs179010 C | 34(63) | 44(73.3) | 116 (59.2) | 1 | 1 |
| TLR7 rs179010 T | 20(37) | 16(26.7) | 80 (40.8) | 0.276/0.822 (0.578–1.170) | 0.015/0.638 (0.444–0.917) |
| N=54 | N=60 | N = 196 | |||
| TLR7 rs2074109 T | 51(94.4) | 57(95) | 186 (94.9) | 1 | 1 |
| TLR7 rs2074109 C | 3(5.6) | 3(5) | 10 (5.1) | 0.869/0.942 (0.461-1.924) | 0.660/0.854(0.424-1.722) |
| N=54 | N=60 | N=196 | |||
| TLR7 rs179009 A | 47(87) | 51(85) | 168(85.7) | 1 | 1 |
| TLR7 rs179009 G | 7(13) | 9(15) | 28(14.3) | 0.799/0.937(0.574-1.532) | 0.614/0.891(0.568-1.396) |
P1/2 value was adjusted for age by logistic regression between AHI-rapid/slow cases and controls.
AHI-rapid, AHI patients with rapid progression: AHI-slow, AHI patients with slow progression.
Bold value indicates the statistical significance.