Table 5.
Haplotype analysis of TLR7 rs179010(C/T), rs2074109(T/C) and rs179009(A/G) in controls and cases/CHI/AHI/AHI-rapid/AHI-slow patients.
| Haplotype | AHI (%) | AHI-rapid (%) | AHI-slow (%) | CHI (%) | Cases (%) | Controls (%) | P a | P b | P c | P d | P e |
|---|---|---|---|---|---|---|---|---|---|---|---|
| CTA | 52.9 | 43.4 | 54.4 | 30.1 | 43.3 | 40.3 | 0.001 | 0.593 | 0.008 | 0.000 | 0.390 |
| TTA | 29.3 | 37.7 | 24.6 | 37.2 | 32.6 | 40.3 | 0.002 | 0.605 | 0.002 | 0.054 | 0.013 |
| CTG | 12.1 | 13.2 | 15.8 | 26.5 | 18.1 | 13.8 | 0.495 | 0.865 | 0.602 | 0.000 | 0.080 |
| CCA | 5.7 | 5.7 | 5.3 | 6.2 | 5.9 | 5.1 | 0.724 | 0.827 | 0.954 | 0.822 | 0.601 |
a
P value calculated between AHI patients and controls.
b
P value calculated between AHI-rapid patients and controls.
c
P value calculated between AHI-slow patients and controls.
d
P value calculated between CHI patients and controls.
e
P value calculated between cases and controls.
Bold value indicates the statistical significance.