Figure 1.

Transferrin transmembrane sequence. Comparison and alignment of the original and the here utilized sequences of the transferrin peptide as well as the prediction of their secondary structure. Sequence alignment was done on the ExPASy webpage using the tool SIM (Miller and Huang, 1991). In order to guide the eye the insertions or deletions are colored blue, substitutions for unsimilar residues are colored magenta and substitutions for similar residues in purpleblue and highlighted in bold. The secondary structure of the peptides was determined using PEP2D (http://crdd.osdd.net/raghava/pep2d/index.html). The part of the peptide predicted to be helical was highlighted by a red background.