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The effects of SG on IL-1β, TNF-a, and IL-6 levels in spinal dorsal horn of CCI Rats. The levels of IL-1β, TNF-a, and IL-6 levels in spinal dorsal horn were detected by ELISA. The levels of IL-1β (A), TNF-a (B), and IL-6 (C) significantly increased in CCI group, but significantly decreased in CCI+SG group. Data are shown as mean ± SD, n = 3. *p<0.05 vs sham group, #p<0.05 and ##p<0.01 vs CCI group.
Abbreviations: SG, sanguinarine; CCI, chronic constriction injury.
