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. 2020 Nov 4;14:4725–4733. doi: 10.2147/DDDT.S276424

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© 2020 Yu et al.

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The effects of SG on the activation of p38 MAPK in spinal dorsal horn of CCI Rats. (A) Immunohistochemical staining of p-p38 protein in spinal dorsal horn. (B) Quantitative analysis of the percentage of positive p-p38 staining in all cells. (C) Western blot analysis of p-p38 protein levels in spinal dorsal horn. (D) Densitometry analysis of relative p-p38 level versus β-actin. Data are shown as mean ± SD, n = 3. Compared with the sham operation group (*P < 0.05), compared with CCI group (^#P < 0.05).

Abbreviations: SG, sanguinarine; CCI, chronic constriction injury.