FIGURE 1.

Muscle overuse-induced cysteine oxidation and subsequent intermediary compound sulfinic acid oxidation compromising the synthesis of taurine and glutathione (GSH). Decreased levels of taurine and GSH may inhibit the glutathionylation resulting in reversible oxidation of cysteine. Further, disturbances in the glutathionylation may cause disturbances in the muscle function like Ca²⁺dyshomeostasis and actin myosin bridge alteration which results in muscle fatigue; taurine supplementation increases the level of taurine in the muscle resulting in regulating Ca²⁺homeostasis and actin myosin bridge activation by controlling ROS and improving exercise performance. CDO, cysteine dioxygenase; CSAD, cysteine sulfinic acid decarboxylase; HTD, hypotaurine dehydrogenase.