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. 2020 Oct 26;13:567084. doi: 10.3389/fnmol.2020.567084

Figure 3.

Figure 3

The soleus muscle of desmin knock-out mice shows a higher degree of fragmentation of their NMJs. (A,B) The extensor digitorum longus or soleus muscle NMJs were categorized in groups according to their number of fragments. The number of NMJs in each group is given as the percentage of the total NMJ number for each genotype. For extensor digitorum longus a total of 96 wild-types and 89 homozygous, for soleus muscle 90 wild-type and 103 homozygous NMJs were counted (n = 3 mouse pairs). Mice were 3–4 months old. Statistical significance was determined by unpaired two-tailed t-test (*P < 0.05, ***P < 0.001). (C,D) The extensor digitorum longus or soleus muscle NMJs were categorized in groups according to their number of fragments. The number of NMJs in each group is given as the percentage of the total NMJ number for each genotype. For extensor digitorum longus a total of 102 wild-types and 95 homozygous, for soleus muscle 99 wild-type and 102 homozygous NMJs were counted (n = 3 mouse pairs). Mice were 7–8 months old. Statistical significance was determined by unpaired two-tailed t-test (*P < 0.05).