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. 2020 Nov;146(5):1165–1179.e11. doi: 10.1016/j.jaci.2020.04.005

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© 2020 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig E5 — Analysis of skin homeostasis in young Rag2^R229Q mice. A, Representative skin section from 20-days-old Rag2^+/+ and Rag2^R229Q mice stained with H&E. Bar = 200 μm. B, Cumulative frequencies of CD45⁺, CD4^+, and CD8⁺ T cells infiltrating the skin. C, Gene expression analysis of Ifng and Cxcl10 in the skin tissue of Rag2^+/+ and Rag2^R229Q mice (n = 6-9 mice/group). Target mRNA was normalized to Actb mRNA. RNA contents are shown as AUs. Plasma levels of (D) CCL17 and CCL22 and (E) LPS-binding protein (LBP). Values are mean ± SEM. ∗P < .05; ∗∗P < .01. Statistical analysis was performed using Mann-Whitney U test.