FIGURE 3.

Select peptides corresponding to the APOBEC3C variant stimulate an mHAg-specific T cell line. An APOBEC3C mHAg-specific T cell line was incubated with an mHAg^neg BLC line pulsed with peptides, including the 11-mer peptide corresponding to the shared region between the 15-mer peptides A3C-A and A3C-B (Figure 2B) and the corresponding wild-type 11-mer and 15-mer peptides. Unpulsed autologous BLCs were included as a negative control, and A3C-A peptide-pulsed autologous BLCs were included as a positive control. Displayed is the percentage of CD3⁺CD8⁺IFN-γ⁺ cells determined by ICS.