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Genomic structures of human GLS1 and GLS2 and alternative transcripts. (A) Two alternative transcripts arise from GLS1, KGA, and glutaminase C (GAC). KGA is the longer isoform with all exons except exon 15, while GAC is the shorter isoform with exons 1–15. (B) Two alternative transcripts arise from GLS2, GAB, and LGA. GAB is the longer isoform with all exons, while LGA is the shorter isoform lack of exon 1.
