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. 2020 Oct 26;14:538404. doi: 10.3389/fnins.2020.538404

FIGURE 7.

FIGURE 7

Effect of nanosilymarin formulation on various biochemical markers like lipid peroxidation (LPO), glutathione (GSH), glutathione reductase (GR), glutathione peroxidase (GPX), superoxide dismutase (SOD), glutathione-S-transferase (GST), and catalase (CAT). Groups shown are control (C), ischemic (I), NS1 (10 μg/kg b.wt), NS2 (100 μg/kg b.wt), NS3 (1,000 μg/kg b.wt), and silymarin (Sil) (100 mg/kg b.wt). A significant increase in LPO content and a decrease in other antioxidant marker content can be seen in the ischemic (I) group in comparison to the control (C) group. Treatment with NS3 restored the marker content significantly. The experiment was conducted for n = 6 data sets, and results are shown as mean ± SEM. Results on comparison with the control group showed a significant difference (###p < 0.001). Results obtained showed significant difference from the ischemic group (p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, and nsp > 0.05).