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. 2020 Oct 26;10:582273. doi: 10.3389/fonc.2020.582273

FIGURE 10.

FIGURE 10

ROS production preceded JNK activation in Cos-provoked apoptosis and autophagy in 769-P cells. (A) Effect of NAC (5 mM) on expressions of phospho-JNK1/2 and total JNK1/2 in 769-P cells exposed to Cos (20 μM) for 24 h. (B) ROS levels in 769-P cells pretreated with SP600125 (10 μM) for 2 h prior to treatment with or without Cos (20 μM). All results are presented as mean ± SD (n = 3). *p < 0.05; **p < 0.01, vs the control.