Table 1.

Qualitative assessment of radioactivity in the posterior pole of the eye of pigmented Abca4^‐/‐ mice after a single intravitreal injection of ³H‐remofuscin

Tissue Sampling time	2hrs	d1	w1	w2	w4	w6	w8	w12	w20
Retina	++	+	‐	‐	‐	‐	‐	‐	‐
RPE	+	++++	++++	+++	+++	++	++	++	++
Bruch´s membrane	++	+	‐	‐	‐	‐	‐	‐	‐
Choroid: red blood cells	++	+	†	‐	‐	‐	‐	‐	‐
Choroid: melanocytes	‐	†	†	†	†	‐	‐	‐	‐

++++ Very high levels of silver grains; +++ high levels of silver grains; ++ moderate levels of silver grains; + low levels of silver grains; † trace of silver grains, ‐ no silver grains (hrs, hours; d, day; w, week).