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. 2020 Nov 3;14(1):100926. doi: 10.1016/j.tranon.2020.100926

Fig. 6.

Fig. 6

Effects of Cisplatin and Fingolimod on tumor-bearing mouse body weight.

A-B. Measure and comparison of mouse body weight upon Cisplatin at 1 mg/kg or Fingolimod at 5 mg/kg treatment i.p. 5 times per week in the 4T1 syngeneic breast cancer model (A) and in the MDA-MB-231-RFP-Luc xenograft breast cancer model (B). Discontinuous orange line highlights treatment beginning.

Two-way ANOVA test (Mixed-effects model) followed by Tukey's multiple comparisons test (vs. control * p ≤ 0.05, ** p ≤ 0.01, **** p ≤ 0.0001; Cisplatin vs. Fingolimod, # p ≤ 0.05; Cisplatin vs. Combination, § p ≤ 0.05; Fingolimod vs. Combination, & p ≤ 0.05). Data represent mean and SD. n = 8 (A) and 6 (B) mice per group at the start of treatment.