Table 2.
SMICs and FICIs results with combinations of PP with azoles against E. dermatitidis biofilms.
| Strain | SMIC50 (μg/ml) | SMIC50 [A/B(μg/ml)] (FICIa) | |||||
|---|---|---|---|---|---|---|---|
| PP | ITC | VRC | POS | PP/ITC | PP/VRC | PP/POS | |
| BMU00028 | 16 | 32 | 16 | 16 | 4/4 (S) | 2/4 (S) | 4/8 (I) |
| BMU00029 | >16 | 32 | 8 | 8 | 8/8 (S) | 4/8 (I) | 2/4 (I) |
| BMU00030 | 8 | 32 | 16 | 16 | 2/16 (I) | 2/4 (S) | 1/4 (S) |
| BMU00031 | 16 | 64 | 8 | 16 | 4/16 (S) | 4/8 (I) | 2/4 (S) |
| BMU00034 | 16 | 32 | 16 | 8 | 4/8 (S) | 4/4 (S) | 4/2 (S) |
| BMU00035 | 8 | 64 | 16 | 16 | 4/16 (I) | 4/8 (I) | 4/2 (I) |
| BMU00036 | 8 | 32 | 8 | 8 | 2/8 (S) | 4/4 (I) | 2/2 (S) |
| BMU00037 | 16 | 32 | 16 | 16 | 4/8 (S) | 4/2 (S) | 4/4 (S) |
| BMU00038 | 16 | 16 | 16 | 16 | 4/2 (S) | 4/4 (S) | 4/4 (S) |
| BMU00039 | >16 | 32 | 8 | 8 | 8/4 (S) | 4/2 (S) | 4/8 (I) |
| BMU00040 | 8 | 32 | 8 | 16 | 2/8 (S) | 2/8 (I) | 4/4 (I) |
| BMU00041 | 16 | 32 | 8 | 8 | 4/8 (S) | 2/8 (I) | 4/2 (S) |
| 109140 | >16 | 32 | 16 | 16 | 4/8 (S) | 4/4 (S) | 4/2 (S) |
| 109144 | 16 | 32 | 16 | 16 | 4/4 (S) | 4/4 (S) | 4/2 (S) |
| 109145 | >16 | 16 | 16 | 16 | 4/2 (S) | 4/8 (I) | 4/4 (S) |
| 109148 | 16 | 32 | 16 | 16 | 4/16 (I) | 8/8 (I) | 2/4 (S) |
| 109149 | 16 | 32 | 16 | 16 | 4/4 (S) | 4/4 (S) | 2/2 (S) |
| 109152 | 16 | 64 | 16 | 32 | 8/16 (I) | 4/8 (I) | 4/4 (S) |
a
S, synergy (FICI of ≤ 0.5); I, no interaction (indifference) (0.5 < FICI ≤ 4).