Table 2.

Association of AKI and in-hospital mortality in critically ill COVID-19 patients

	Unadjusted		Adjusted
	HR (95% CI)	p value	HR (95% CI)	p value
28-Days mortality
Non-AKI Mild AKI Severe AKI	1.00 (reference) 1.35 (0.46–3.93) 2.78 (l.18–6.55)	0.582 0.019	1.00 (reference) 0.87 (0.38–1.99) 1.68 (0.93–3.02)	0.745 0.086
In-hospital mortality
Non-AKI Mild AKI Severe AKI	1.00 (reference) 1.34 (0.46–3.90) 4.60 (1.77–12.01)	0.588 0.002	1.00 (reference) 0.89 (0.41–1.91) 1.82 (1.06–3.13)	0.761 0.029

AKI, acute kidney injury; COVID-19, coronavirus disease 2019; HR, hazard ratio; 95% CI, 95% confidence interval. HRs were obtained in multivariate Cox proportional hazards model after adjustment for age, sex, hypertension, sequential organ failure assessment (SOFA) score, platelet count and lactose dehydrogenase.