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Bladder activity was induced in mice during continuous infusion cystometry (30 μl/min) with pH 6.3 saline followed by pH 6.0 saline containing vehicle (A) or A-317567 (100 μM) (B). Intravesical perfusion of neither A-317567 nor vehicle produced effects on bladder activity. SAL, saline (pH 6.0) infusion.
