TABLE 2.
PT (mmHg) | MVP (mmHg) | CPP (mmHg) | RP (mmHg) | 1st PD (s) | 2nd PD (s) | BCD (s) | ICI (s) | BCP (μl/mmHg) | |
SAL (pH 6.3) | 4.8 ± 0.2 | 24.7 ± 1.1 | 14.5 ± 1.8 | 1.1 ± 0.1 | 10.1 ± 0.9 | 15.6 ± 0.9 | 25.7 ± 0.6 | 392.1 ± 33.0 | 55.3 ± 4.2 |
AA (pH 3.0) | 3.9 ± 0.2** | 17.3 ± 1.2*** | 8.3 ± 0.8** | 1.7 ± 0.1** | 8.2 ± 1.2 | 10.8 ± 1.4** | 19.0 ± 2.1** | 76.0 ± 8.5**** | 16.5 ± 1.2**** |
Values are means ± SEM for 12 mice. Comparisons between SAL and AA by unpaired t test: **P < 0.01, ***P < 0.001, ****P < 0.0001. PT, pressure threshold for inducing micturition contraction; MVP, maximal voiding pressure; CPP, closing peak pressure; RP, resting pressure; 1st PD, 1st phase duration of bladder contraction; 2nd PD, 2nd phase duration of bladder contraction; BCD, bladder contraction duration; ICI, intercontraction interval; BCP, bladder compliance; SAL, saline infusion; AA, acetic acid infusion.