Table 1.
Clinical characteristics of patients with SNV at initial diagnosis.
| Total patients n = 2,660 | Patient with TB n = 51 | Patient without TB n = 2,609 | P-value | |
|---|---|---|---|---|
| Age, years | 57.5 ± 16.9 | 59.1 ± 18.1 | 57.5 ± 16.8 | 0.502 |
| Sex, n (%) | 0.208 | |||
| Male | 1,203 (45.2) | 28 (54.9) | 1,175 (45.0) | |
| Female | 1,457 (54.8) | 23 (45.1) | 1,434 (55.0) | |
| Diagnosis [ICD-10 code], n (%) | 0.037 | |||
| MPA | 925 (34.8) | 17 (33.3) | 908 (34.8) | |
| GPA | 583 (21.9) | 17 (33.3) | 566 (21.7) | |
| EGPA | 593 (22.3) | 4 (7.8) | 589 (22.6) | |
| PAN | 559 (21.0) | 13 (25.5) | 546 (20.9) | |
| Follow-up duration, years | 3.3 ± 2.7 | 1.4 ± 2.0 | 3.3 ± 2.7 | <0.001 |
| Type of TB, n (%) | ||||
| Pulmonary TB [A15, 16, 19] | 43 (84.3) | 43 (84.3) | ||
| Extrapulmonary TB [A17-18] | 8 (15.7) | 8 (15.7) | ||
| Insurance status, n (%) | 1.000 | |||
| National Health Insurance | 2,550 (95.9) | 49 (96.1) | 2,501 (95.9) | |
| Medical Aid | 110 (4.1) | 2 (3.9) | 108 (4.1) | |
| COMORBIDITIES [ICD-10 CODE], n (%) | ||||
| Hypertension [I10-15] | 1,255 (47.2) | 27 (52.9) | 1,228 (47.1) | 0.490 |
| Diabetes mellitus [E10-14] | 899 (33.8) | 19 (37.3) | 880 (33.7) | 0.706 |
| Chronic kidney disease [N18] | 349 (13.1) | 11 (21.6) | 338 (13.0) | 0.111 |
| Chronic obstructive pulmonary disease [J43-44] | 427 (16.1) | 9 (17.7) | 418 (16.0) | 0.904 |
| HIV infection [B20-24] | 0 (0.0) | 0 (0.0) | 0 (0.0) | n/a |
| Silicosis [J62] | 0 (0.0) | 0 (0.0) | 0 (0.0) | n/a |
| IMMUNOSUPPRESSIVE AGENTS USAGE, n (%) | ||||
| Glucocorticoid usage ≥ 12 month | 1,246 (46.8) | 10 (19.6) | 1,236 (47.4) | <0.001 |
| Cyclophosphamide | 1,153 (43.4) | 18 (35.3) | 1,135 (43.5) | 0.304 |
| Azathioprine | 992 (37.3) | 10 (19.6) | 982 (37.6) | 0.013 |
| Methotrexate | 433 (16.3) | 7 (13.7) | 426 (16.3) | 0.759 |
| Rituximab | 258 (9.7) | 3 (5.9) | 255 (9.8) | 0.476 |
Values are expressed as mean (standard deviation) or in number (percentages).
SNV, systemic necrotizing vasculitides; TB, tuberculosis; ICD, international classification of diseases; MPA, microscopic polyangiitis; GPA, granulomatosis with polyangiitis; EGPA, eosinophilic granulomatosis with polyangiitis; PAN, polyarteritis nodosa; HIV, human immunodeficiency virus.