Table 3.
Logistics regression analysis for OR value.
| Univariate analysis |
Severe/critical versus mild/moderate |
ICU versus non-ICU |
||
|---|---|---|---|---|
| Variables | OR | p | OR | p |
| Age | 1.03 (1.01–1.06) | 0.015 | 1.04 (1.01–1.07) | 0.022 |
| Dyspnea | 12.57 (5.64–28.02) | <0.001 | 12.19 (4.35–34.18) | <0.001 |
| Cluster exposure history | 0.91 (0.39–2.14) | 0.836 | – | – |
| Hypertension | 2.77 (1.17–6.54) | 0.020 | – | – |
| COPD | – | – | 10.61 (1.41–78.88) 0.022 | 0.022 |
| Poor appetite | 3.16 (1.22–8.17) | 0.018 | 4.05 (1.28–12.80) | 0.017 |
| Fatigue | 3.04 (1.43–6.45) | 0.004 | – | – |
| Two lung involvement | 2.27 (0.64–8.01) | 0.204 | – | – |
| WBC >10 × 109/L | 10.75 (2.56–42.21) | 0.001 | 5.50 (1.26–23.97) | 0.023 |
| Neutrophil | 1.30 (1.06–1.59) | 0.011 | ||
| Lymphopenia <0.8 × 109/L | 4.30 (0.25–9.02) | <0.001 | 5.74 (2.20–14.98) | <0.001 |
| PT | 1.32 (1.02–1.72) | 0.037 | ||
| CK >200 U/L | 4.42 (1.31–14.93) | 0.017 | – | – |
| CK-MB >23 U/L | 4.23 (1.39–12.87) | 0.011 | – | – |
| D-dimer >0.5 mg/L | 2.69 (1.23–5.90) | 0.013 | 7.18 (2.41–21.36) | <0.001 |
| Albumin <35 g/L | 9.86 (4.25–22.89) | <0.001 | 11.35 (3.76–34.28) | <0.001 |
| ALT >40 U/L | 3.39 (1.49–7.70) | 0.004 | 7.39 (2.78–19.67) | <0.001 |
| AST >40 U/L | 3.32 (1.38–7.99) | 0.007 | 6.11 (2.22–16.80) | <0.001 |
| LDH >250 U/L | 6.75 (2.80–16.28) | <0.001 | 12.29 (4.36–34.63) | <0.001 |
| CRP >10 mg/L | 3.28 (1.35–8.01) | 0.009 | 3.35 (0.92–12.29) | 0.068 |
| Multivariate analysis | ||||
| Dyspnea | 19.48 (5.65–67.19) | <0.001 | 8.88 (1.54–51.07) | 0.014 |
| COPD | – | – | 31.80 (2.21–457.65) | 0.011 |
| D-dimer | – | – | 8.37 (1.33–52.86) | 0.024 |
| Albumin | 3.36 (1.06–10.67) | 0.040 | – | – |
| ALT | 6.02 (1.50–24.19) | 0.011 | 28.76 (4.19–197.24) | 0.001 |
| LDH | – | – | 9.95 (1.83–54.09) | 0.008 |
ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK, creatine kinase; CK-MB, creatine kinase-MB; COPD, chronic obstructive pulmonary disease; CRP, C-reactive protein; ICU, intensive care unit; LDH, lactate dehydrogenase; OR, odds ratio; PT, prothrombin time; WBC, white blood cell.