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. 2020 Nov 5;12:1758835920970049. doi: 10.1177/1758835920970049

Table 3.

Univariate and multivariate logistic regression analyses for progression-free survival in non-small cell lung cancer patients treated with immune checkpoint inhibitors after propensity score matching.

Variable Category Univariate analysis
Multivariate analysis
HR (95% CI) p-value HR (95% CI) p-value
Age, years ⩾61 versus <61 0.78 (0.59−1.03) 0.09 0.81 (0.60−1.08) 0.16
Sex Female versus male 1.33 (0.97−1.83) 0.07 1.35 (0.87−2.07) 0.17
Smoking history Yes versus no 0.92 (0.69−1.22) 0.57 1.24 (0.83−1.85) 0.28
Histology Squamous versus non-squamous 0.87 (0.64−1.17) 0.36 0.80 (0.58−1.10) 0.18
Stage IV versus III 0.98 (0.66−1.47) 0.96 0.81 (0.52−1.24) 0.34
ECOG PS ⩾2 versus 0−1 1.12 (0.61−2.03) 0.71 1.07 (0.56−2.05) 0.82
Treatment type Combination therapy versus monotherapy 0.75 (0.57−0.99) <0.05 0.73 (0.54−0.99) <0.05
Prior lines of therapy 1 line versus 2 lines versus ⩾3 lines 1.24 (1.04−1.42) 0.01 1.16 (0.9−1.42) 0.13
Brain metastasis Yes versus no 1.70 (1.18−2.44) <0.01 1.40 (0.95−2.05) 0.08
Baseline Hb, g/L ⩾110 versus <110 0.63 (0.47−0.83) <0.01 0.67 (0.50−0.91) 0.01

CI, confidence interval; ECOG PS, Eastern Cooperative Oncology Group Performance Status; Hb, hemoglobin; HR, hazard ratio.