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. 2020 Jul 6;68(11):733–746. doi: 10.1369/0022155420937370

Figure 1.

Figure 1.

Schematic depiction of the mechanisms of action of decorin-evoked endothelial cell autophagy (left) or decorin-mediated tumor cell mitophagy (right) on distinct compartments within the tumor such as the tumor microenvironment and tumor parenchyma (center). Please consult the manuscript for additional details. Abbreviations: AMPK, activated protein kinase; GFP, green fluorescent protein; mtDNA, mitochondrial DNA; mTOR, mammalian target of rapamycin; OXPHOS, oxidative phosphorylation; Peg3, paternally expressed gene 3; TFEB, transcription factor EB; VDAC1, voltage-dependent anion channel 1; VEGFR2, vascular endothelial growth factor receptor 2.