Table 1.
Overview of commercially available software applications for automated and semi-automated medical image analysis for acute stroke diagnostics (Descriptions are based on information provided by the companies on their official websites. Some companies also offer algorithm outside the ischemic stroke field; we listed them for completion but do not further discuss those)
| Company | Software | Description |
|---|---|---|
| Aidoc | Aidoc Head | triages stroke patients using non-contrast CT scans by flagging suspected intracranial haemorrhages and highlights cases that require immediate attention in worklist |
| Apollo Medical Imaging Technology | CT Perfusion: Stroke | CTP stroke module is a part of MIStar software package. It generates brain perfusion maps using deconvolution algorithms together with Apollo’s noise reduction and motion artefact correction technologies |
| DSC-MRI: Stroke | DSC-MRI perfusion module is a part of MIStar software. It features both parametric curve analysis and deconvolution algorithm for perfusion maps with easy identification of arterial input function | |
| Brainomix | e-ASPECTS | assess the ASPECTSa score and volume of ischemia in non-contrast CT images |
| e-CTA | standardizes the assessment of collaterals in CTA scans | |
| inferVISION | AI-CT (head) | gets information about type of stroke (haemorrhagic or ischemic), determines location, volume and severity of haemorrhagic strokes |
| iSchemaView | RAPID CTA | automatically provides CTA maps and identifies brain regions with reduced blood vessel density |
| RAPID CTP | provides cerebral perfusion maps | |
| RAPID MRI | provides fully automated diffusion and perfusion maps | |
| RAPID ASPECTS | automatically identifies and scores regions with early ischemic changes using ASPECTS | |
| JLK Inspection | JBS-01 K | Ischemic stroke subtype (TOASTb) classification solution based on MR images and clinical information data |
| JBS-02 K | Ischemic stroke severity (NIHSSc) prediction solution based on MR images, clinical information data and 3D hybrid artificial neural network technology | |
| JBS-03 K | Ischemic stroke prognosis (3-month mRSd) prediction solution based on MR images, clinical information data and 3D hybrid artificial neural network technology | |
| JBS-04 K | Haemorrhagic stroke detection and classification solution based on CT images and 3D hybrid artificial neural network technology | |
| JBS-05 K | Hyperacute ischemic stroke detection solution based on CT images and clinical information data | |
| JBS-06 K | Hyperacute ischemic stroke detection solution based on MRI, clinical information data and 3D hybrid artificial neural network technology | |
| JBA-01 K | Aneurysm detection solution based on MR angiography, clinical information data and 3D hybrid artificial neural network technology | |
| Max-Q AI | AccipioDx | diagnostic tool that rules out the presence of intracranial haemorrhage in non-contrast CT scans |
| mbits | mRay-Modul veocore | Perfusion analysis tool |
| Nico.lab | StrokeViewer | provides analysis of relevant biomarkers from stroke imaging (NCCT, CTA, dynamic CTA and follow-up imaging). The following have been clinically validated: Haemorrhage detection and quantification, thrombus identification and evaluation, collateral assessment, follow-up infarct volume quantification, ASPECTS (in development) |
| Olea Medical | Olea Sphere | automatically computes core, penumbra and mismatch ratio in CT and MR perfusion images |
| Qure.ai | qER | detects critical abnormalities such as bleeds, fractures mass effect and midline shift, localizes them and quantifies their severity in head CT |
| qQuant | suite of quantification and progression monitoring products for CT and MRI scans (e.g. brain tumour volume) | |
| Viz.ai | Viz LVO | automatically identifies and triages suspected large vessel occlusion (LVO) strokes |
| Viz CTP | automatically analyse CT perfusion images | |
| Zebra Medical Vision | AI1 | All-In-One (AI1) Application with included algorithm for intracranial haemorrhage detection. AI1 detects also other medical conditions like low bone mineral density, vertebral fractures and more |
a ASPECTS: Alberta stroke programme early CT score
b TOAST: Trial of Org 10,172 in Acute Stroke Treatment
c NIHSS: NIH Stroke Scale
d mRS: modified Ranking Scale