Table 2.

A brief list of actively recruiting or completed large clinical trials using RApid processing of PerfusIon and Diffusion [RAPID] software (iSchemaView, Menlo Park, USA) for assessment of CT- and MRI- perfusion images

Trial Name	RAPID	Number of Patients	Status	Reference
DWI or CTP Assessment with Clinical Mismatch in the Triage of Wake-Up and Late Presenting Strokes Undergoing Neurointervention with Trevo (DAWN)	imaging selection for 100% of patients	206	Completed	[72]
The diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study	imaging selection for 100% of patients	74	Completed	[61]
The diffusion and perfusion imaging evaluation for understanding stroke evolution 3(DEFUSE 3) study	imaging selection for 100% of patients	182	Completed	[38]
Extending the Time for Thrombolysis in Emergency Neurological Deficits (International) (EXTEND)	imaging selection for 100% of patients	225	Completed	[73]
Extending the Time for Thrombolysis in Emergency Neurological Deficits - Intra-Arterial (EXTEND-IA)	imaging selection for 100% of patients	70	Completed	[74]
FRench Acute Cerebral Multimodal Imaging to Select Patient for MEchanical Thrombectomy (FRAME)	imaging selection for 100% of patients	Estimated Enrollment: 220 participants	Enrolling	ClinicalTrials.gov Identifier: NCT03045146
Solitaire™ With the Intention For Thrombectomy as PRIMary Endovascular Treatment (SWIFT PRIME) Trial	imaging selection for 100% of patients	196	Completed	[75]