Fig. 3.

Neuroimaging of motor network reorganization after a first-ever stroke. a fMRI activity maps associated with movements of the paretic hand at different time points post-stroke. Recovery of hand motor function (here: maximum grip strength) is associated with fMRI signal increases early after stroke, the latter returning to levels observed in healthy controls with good functional recovery. From Rehme et al. [52, 53], with permission. b Impact of motor impairment and activity changes post-stroke. From Rehme et al. [52, 53], with permission. c Connectivity changes correlated with motor outcome. Green arrows: Increases indicate good functional motor outcome. Red arrow: Patients developing inhibitory influence from contralesional upon ipsilesional M1 activity feature poor functional motor outcome