Table 4.
Correlation of levels of solubility ratios of poly-GP, poly-GA and poly-GR with parameters of clinical severity (age at death, age of onset, disease duration)
| Ratio soluble DPR/total | Poly-GP | Poly-GA | Poly-GR |
|---|---|---|---|
| Age at death | |||
| FC | − 0.35 | 0.20 | 0.28 |
| TC | − 0.67 (0.015) | − 0.05 | 0.15 |
| OC | − 0.73 (0.006) | − 0.21 | − 0.23 |
| Cb | − 0.43 | 0.00 | 0.25 |
| Age of onset | |||
| FC | − 0.61 (0.05) | − 0.18 | 0.32 |
| TC | − 0.73 (0.006) | − 0.08 | − 0.03 |
| OC | − 0.78 (0.002) | − 0.27 | − 0.23 |
| Cb | − 0.49 (0.09) | 0.14 | 0.40 |
| Disease duration | |||
| FC | − 0.09 | 0.24 | − 0.22 |
| TC | − 0.26 | 0.03 | 0.05 |
| OC | − 0.36 | − 0.07 | 0.03 |
| Cb | − 0.05 | − 0.06 | − 0.38 |
Spearman’s rank correlation coefficient ρ is shown for correlation of soluble ratio (over total) of poly-GP, poly-GA and poly-GR in frontal cortex (FC), temporal cortex (TC), occipital cortex (OC) and cerebellum (Cb) with age at death, age of onset and disease duration. Correlation coefficients with statistical significance are shown in bold. For all values showing a statistically significant or a trend of correlation, p-values are specified between brackets