Table 2.

Genetic polymorphism and tests of neutrality in the N-terminal and C-terminal non-repeat regions of global VK210 variants

Region	Country	n	K	S	Eta	H	Hd ± SD	π ± SD	dN-dS	Tajima’s DP value	Fu and Li’s DP value	Fu and Li’s FP value
N-terminal	Myanmar	143	0.098	5	6	7	0.096 ± 0.034	0.0024 ± 0.0009	0.0008	− 1.9359c	− 3.9086b	− 3.8409b
	Cambodia	31	0.125	1	1	2	0.125 ± 0.077	0.0030 ± 0.0018	0.0039	− 0.7737a	0.5907a	0.2450a
	India	79	1.972	23	28	28	0.661 ± 0.063	0.0470 ± 0.0074	− 0.0909	− 2.0261c	− 1.3952a	− 1.9514e
	Iran	39	0	0	0	1	0	0	0	0	0	0
	South Korea	39	0.051	1	1	2	0.051 ± 0.048	0.0012 ± 0.0011	0.0016	− 1.1264a	− 1.7662a	− 1.8293a
	Brazil	41	0.049	1	1	2	0.049 ± 0.046	0.0012 ± 0.0011	− 0.0059	− 1.1219a	− 1.7816a	− 1.8406a
	Mexico	11	0	0	0	1	0	0	0	0	0	0
	Sudan	30	0	0	0	1	0	0	0	0	0	0
	Vanuatu	21	0	0	0	1	0	0	0	0	0	0
C-terminal	Myanmar	143	0.209	10	11	11	0.186 ± 0.044	0.0035 ± 0.0009	− 0.0035	− 2.2251d	− 3.5089b	− 3.6329b
	Cambodia	31	0	0	0	1	0	0	0	0	0	0
	India	79	0.276	8	9	6	0.123 ± 0.051	0.0043 ± 0.0020	− 0.0149	− 2.1953d	− 4.4419b	− 4.3524b
	Iran	39	0	0	0	1	0	0	0	0	0	0
	South Korea	39	0.103	2	2	3	0.101 ± 0.065	0.0008 ± 0.0005	− 0.0037	− 1.4889a	− 2.4148e	− 2.4864e
	Brazil	41	0	0	0	1	0	0	0	0	0	0
	Mexico	11	0	0	0	1	0	0	0	0	0	0
	Sudan	30	0.067	1	1	2	0.067 ± 0.061	0.0009 ± 0.0008	− 0.0041	− 1.1470a	− 1.6821a	− 1.7655a
	Vanuatu	21	0	0	0	1	0	0	0	0	0	0

n number of analysed sequences, K avarage number of nucleotide differences, S number of segregating sites, Eta total number of mutations, H number of haplotypes, Hd haplotype diversity, π observed average pairwise nucleotide diversity, SD standard deviation, dN rate of non-synonymous mutations, dS rate of synonymous mutations

^aP > 0.1

^bP < 0.02

^cP < 0.05

^dP < 0.01

^e0.05 < P < 0.1