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. 2020 Sep 4;19:303. doi: 10.1186/s12936-020-03366-7

Table 3.

Genetic polymorphism and tests of neutrality in N-terminal and C-terminal regions of global pvcsp VK247 variants

Region Country n K S Eta H Hd ± SD π ± SD dN-dS Tajima’s DP value Fu andLi’s Dvalue Fu and Li’s Fvalue
N-terminal Myanmar 28 0.405 1 2 3 0.405 ± 0.094 0.0090 ± 0.0021 0.0117 − 0.4445a − 0.7114a − 0.7369a
Cambodia 10 0.2 1 1 2 0.200 ± 0.154 0.0029 ± 0.0022 0.0038 − 1.1117a − 1.2434a − 1.3467a
Iran 11 1.309 3 3 2 0.436 ± 0.133 0.0190 ± 0.0058 − 0.0543 0.9518a 1.1271a 1.2185a
Mexico 8 0 0 0 1 0 0 0 0 0 0
Colombia 25 0 0 0 1 0 0 0 0 0 0
C-terminal Myanmar 28 0.495 6 6 6 0.331 ± 0.114 0.0067 ± 0.0027 − 0.0150 − 1.9719c − 2.5946c − 2.8039c
Cambodia 10 0.400 2 2 2 0.200 ± 0.154 0.0039 ± 0.0030 − 0.0172 − 1.4009a − 1.5866a − 1.7190a
Iran 11 0 0 0 1 0 0 0 0 0 0
Mexico 8 0 0 0 1 0 0 0 0 0 0
Colombia 25 0.500 2 2 3 0.44 ± 0.095 0.0039 ± 0.0010 0.0017 − 0.1215a − 0.6754a − 0.6012a

n number of analysed sequences, K average number of nucleotide differences, S number of segregating sites, Eta total number of mutations, H number of haplotypes, Hd haplotype diversity, π observed average pairwise nucleotide diversity, SD standard deviation, dN rate of non-synonymous mutations, dS rate of synonymous mutations

aP > 0.1

bP < 0.02

cP < 0.05

dP < 0.01

e0.05 < P < 0.1