Abbreviations	Definition
BHT	butylhydroxytoluene
CE	cholesteryl ester
Cept	ethanolamine phosphotransferase
CER	ceramide
CerS	ceramide synthase
Chpt	choline phosphotransferase
CLE	Chrysanthemum morifolium Ramat leaf extracts
CM	Chrysanthemum morifolium Ramat
CVD	cardiovascular disease
DAG	diacylglycerol
DES1	dihydroceramide desaturase
HFD	high-fat diet
HPLC	high-performance liquid chromatography
IS	internal standard
kdsr	3-ketodihydrosphingosine reductase
LCAT	lecithin-cholesterol acyltransferase
LC-MS/MS	liquid chromatography coupled with tandem mass spectrometry
LDL	low-density lipoprotein
LPC	lysophosphatidylcholine
LPE	lysophosphatidylethanolamine
LU	HFD plus luteolin 0.003% diet
MTBE	methyl-tert-butyl ether
ND	normal diet
PC	phosphatidylcholine
PCA	principal component analysis
PE	phosphatidylethanolamine
PEMT	Phosphatidylethanolamine N-methyltransferase
PLA2	phospholipase A2
PLS-DA	partial least squares-discriminant analysis
PPAR	peroxisome proliferator-activated receptor
QC	quality control
Sgms	sphingomyelin synthase
SM	sphingomyelin
SPT	serine palmitoyltransferase
SRM	selected reaction monitoring
TAG	triacylglycerol
TNF	tumor necrosis factor
T2DM	type 2 diabetes mellitus
WAT	white adipose tissue