Table 1.
Sensitivities, specificities, and accuracies of eight severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin G (IgG) or total antibody assays calculated from the results of two reference tests. The highest values are shown in green; the lowest values are marked in red.
| (%) | Sensitivity | Sensitivity | Specificity 3 | Accuracy | Accuracy |
|---|---|---|---|---|---|
| Reference test | PCR 1 | PRNT 2 | PCR 1 | PRNT 2 | |
| Assay\n | 26 | 27 | 100 | 126 | 127 |
| Abbott | 96.2 | 96.3 | 99.0 | 98.4 | 98.4 |
| Diasorin | 84.6 | 88.9 | 96.0 | 93.7 | 94.5 |
| Epitope | 80.8 | 92.6 | 100.0 | 96.0 | 98.4 |
| Euroimmun | 80.8 | 88.9 | 97.0 | 93.7 | 95.3 |
| Mikrogen | 88.5 | 96.3 | 98.0 | 96.0 | 97.6 |
| Roche | 88.5 | 96.3 | 99.0 | 96.8 | 98.4 |
| Viramed | 88.5 | 96.3 | 99.0 | 96.8 | 98.4 |
| Virion-Serion | 96.2 | 96.3 | 100.0 | 99.2 | 99.2 |
1 SARS-CoV-2 RNA was previously detected in the PCR test. 2 SARS-CoV-2-neutralizing antibodies with a titer >1:10 were demonstrated in the plaque reduction neutralization test (PRNT). 3 100 stored sera from 2018/2019.